• Test Code:
    1300
  • Department:
  • Test Synonyms:
    DNA StorageDNA BankingDNA Storage for Future Testing
  • CPT Code(s):
    83890
Background:

The storage of purified high molecular weight DNA is applicable in situations where a confirmed or suspected genetic condition is evident and the possibility of future testing will be critically dependent on the analysis of specific samples.  This procedure is particularly important in cases where an affected individual may be medically unstable.  DNA will be extracted from the submitted specimen and stored for a minimum of ten (10) years.  Molecular testing of stored DNA samples may only be performed with the written authorization of the patient or the legal designate.  Release of stored DNA for molecular testing at another institution will follow written authorization provided by the patient or the legal designate which specifies the third party testing facility and their address.  Laboratory policy for specimen handling, storage, and subsequent release of isolated DNA follow guidelines of the American College of Medical Genetics and adhere to provisions found under the Oregon Genetic Privacy Act.

Methodology:

DNA isolation from submitted specimens will be performed according to accepted protocols as evidenced by the published literature.  DNA yield is quantitated and purity is estimated by spectrophotometric evaluation of 260 nm/280 nm ratio.  DNA will be inventoried and stored for a minimum of 10 years in a manner designed to preserve the viability and suitability of the specimen for future medical or diagnostic purposes.

Specimen Requirements:

  • Blood:  6.0 mL whole blood in EDTA (purple-top) or ACD (yellow-top) tube
  • Other tissues may be acceptable for DNA storage.  Please call Client Services at (855) 535-1522 before sending specimens other than blood.
  • A requisition form and DNA Storage Consent form (ACC-FRM-003.01 DNA Storage Consent) must accompany all specimens.  Contact Client Services with questions.
  • For DNA withdrawal, please fill out DNA Storage Withdrawal Form.  Contact Client Services with questions.

Test Performed (Days):

Daily, M – F

Turn Around Time:

Not Applicable

Shipment Sensitivity Requirements:

Package and ship specimen to remain cold, but not frozen.  Ship via overnight express, using the FedEx priority overnight label provided.  Contact Client Services for shipping kits and instructions at (855) 535-1522.

References:

Additional Info:

  • DNA preparation and storage of specimens from individuals or families interested in molecular analysis at some future date.
  • DNA preparation and storage from individuals for whom future sample collection may be problematic.
  • Specimen handling and DNA storage in a licensed and accredited CLIA Laboratory.

The Knight Cancer Institute at Oregon Health & Science University is a pioneer in the field of precision cancer medicine. The institute's director, Brian Druker, M.D., helped prove it was possible to shut down just the cells that enable cancer to grow. This breakthrough has made once-fatal forms of the disease manageable and transformed how cancer is treated. The OHSU Knight Cancer Institute is the only National Cancer Institute-designated Cancer Center between Sacramento and Seattle – an honor earned only by the nation's top cancer centers. It is headquarters for one of the National Cancer Institute's largest research collaboratives, SWOG, in addition to offering the latest treatments and technologies as well as hundreds of research studies and clinical trials.

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