Molecular Genetics

The molecular genetics laboratory primarily focuses on inherited single gene disorders, providing essential information to genetic counselors, geneticists, and other physicians. Common single gene genetic disorders assessed in the lab on a gene-by-gene basis include:

Gene testing by next generation sequencing panels and array CGH is available for multiple rare disorders, such as: 

Additionally, the lab offers a clinical research exome (‘medical exome’) complimented by an exon-level exome microarray.

The laboratory has extensive experience with Sanger sequencing, MLPA, melting curve analysis, Southern blot, etc and thus has the ability to rapidly confirm any findings with an anxillary technique.  Furthermore,  our experience with these techniques positions us to provide custom and targeted analyses when requested. 


Knight Diagnostic Laboratories specializes in providing the most appropriate test panels to address clinical needs. Our Medical Directors are always available to provide expert consultation.

The Knight Cancer Institute at Oregon Health & Science University is a pioneer in the field of precision cancer medicine. The institute's director, Brian Druker, M.D., helped prove it was possible to shut down just the cells that enable cancer to grow. This breakthrough has made once-fatal forms of the disease manageable and transformed how cancer is treated. The OHSU Knight Cancer Institute is the only National Cancer Institute-designated Cancer Center between Sacramento and Seattle – an honor earned only by the nation's top cancer centers. It is headquarters for one of the National Cancer Institute's largest research collaboratives, SWOG, in addition to offering the latest treatments and technologies as well as hundreds of research studies and clinical trials.

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