The Hematologic Malignancy team at the Knight Diagnostic Laboratories performs diagnostic and clinically actionable tests developed at Oregon Health & Science University.  The department utilizes a variety of molecular platforms which allows testing to be developed using the most appropriate technology available for the application.  Testing includes quantitative real-time PCR, high resolution melting curve (HRM) analyses, Sanger sequencing, and Next Generation sequencing.
Showing Results 1 to 10 of 31.

B-Cell IGH Gene Rearrangement

  • Test Code:
    4071 LAB103463 LAB103464 LAB103465
  • Department:
  • Test Synonyms:
    Immunoglobulin (IgH) Gene Rearrangement Immunoglobulin (IgH) Clonality Immunoglobulin light chain clonality Gene rearrangements for B-cell lymphoma B cell gene rearrangement for clonality
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B-Cell IGK Gene Rearrangement

  • Test Code:
    4072 LAB103466 LAB103467 LAB103468
  • Department:
  • Test Synonyms:
    Kappa gene rearrangement Kappa gene clonality Gene rearrangements for B-cell lymphoma B cell gene rearrangement for clonality
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BCR-ABL Kinase Domain Mutations/ABL Sequencing (Qualitative)

  • Test Code:
    4020 LAB102696 LAB102697 LAB103666
  • Department:
  • Test Synonyms:
    Imatinib resistance mutation testing Tyrosine kinase inhibitor resistance mutation testing; ABL mutation testing for chronic myeloid leukemia T3151 Mutation
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BCR-ABL RNA PCR Quantitation for Leukemia

  • Test Code:
    4080 LAB00784 LAB103665 LAB100589
  • Department:
  • Test Synonyms:
    BCR-ABL RNA Philadelphia chromosome fusion transcript levels determination BCR-ABL PCR CML monitoring CML minimal residual disease
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BTK Inhibitor Acquired Resistance Panel

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BTK, Exon 14, Sequencing

  • Test Code:
    4125 LAB101810 LAB101816 LAB101819
  • Department:
  • Test Synonyms:
    BTK BTK exon 14 ibrutinib resistance mutation
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CALRETICULIN (CALR) Gene Mutations in Myeloproliferative Neoplasms

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cKIT - AML

  • Test Code:
    4206
  • Department:
  • Test Synonyms:
    KIT (cKIT) Mutation Screening for Acute Myelogenous Leukemia (exons 8 & 17)
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CXCR4 Mutation Testing

  • Test Code:
    4133
  • Department:
  • Test Synonyms:
    Lymohoplasmacytic lymphoma Waldenstroms WM LPL
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Engraftment (Chimerism) Analysis for Allogeneic Hematopoietic Stem Cell

  • Test Code:
    4380 (Donor Pre-Transplant) 4382 (Recipient Pre-Transplant) 4388 (Post-Transplant Chimerism) 4390 (Post-Transplant Sorted Cell Chimerism) LAB00787 LAB101769 LAB102618 LAB102668
  • Department:
  • Test Synonyms:
    Pretransplant DNA storage Post-transplant DNA for engraftment study DNA from sorted cells for chimerism study
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The Knight Cancer Institute at Oregon Health & Science University is a pioneer in the field of precision cancer medicine. The institute's director, Brian Druker, M.D., helped prove it was possible to shut down just the cells that enable cancer to grow. This breakthrough has made once-fatal forms of the disease manageable and transformed how cancer is treated. The OHSU Knight Cancer Institute is the only National Cancer Institute-designated Cancer Center between Sacramento and Seattle – an honor earned only by the nation's top cancer centers. It is headquarters for one of the National Cancer Institute's largest research collaboratives, SWOG, in addition to offering the latest treatments and technologies as well as hundreds of research studies and clinical trials.

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