The Knight Diagnostic Laboratories include a molecular translational research lab and three genetics laboratories specializing in molecular genetics, cytogenetics, and FISH analyses.
Knight Diagnostic Laboratories’ expertise in genetics and molecular pathology join together in the diagnosis of inherited cancer syndromes. While most cancer is sporadic, 5-10% of all cancers are inherited. Syndromes may have either recessive or dominant inheritance. Oregon Health and Science University is a center of excellence for Fanconi anemia, a recessive inherited syndrome. Knight Diagnostic Laboratories has been providing comprehensive molecular analyses of the Fanconi genes and other disorders for many years. All inherited cancer syndrome testing is performed and interpreted as described for genetic rare disorders by American College of Medical Genetics.
The Knight Cancer Institute at Oregon Health & Science University is a pioneer in the field of precision cancer medicine. The institute's director, Brian Druker, M.D., helped prove it was possible to shut down just the cells that enable cancer to grow. This breakthrough has made once-fatal forms of the disease manageable and transformed how cancer is treated. The OHSU Knight Cancer Institute is the only National Cancer Institute-designated Cancer Center between Sacramento and Seattle – an honor earned only by the nation's top cancer centers. It is headquarters for one of the National Cancer Institute's largest research collaboratives, SWOG, in addition to offering the latest treatments and technologies as well as hundreds of research studies and clinical trials.
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