KNIGHT DIAGNOSTIC LABORATORIES
Laboratory Shipping Address: 2525 SW 3rd. Avenue, Suite 350 Portland, OR 97201
Correspondence Address: 3181 SW Sam Jackson Park Road, Mailstop MP-350 Portland, OR 97239
Phone: 855-KDL-1LAB (535-1522) - Fax: 855-KDL-1FAX (535-1329)
  • Test Code:
    2040
  • Department:
    Molecular Genetics
  • Test Synonyms:
    Homocysteine, DNA Test • Methylene Tetrahydrofolate Reductase • MTHFR (C677T)
  • CPT Code(s):
Background:

In an effort to provide the most up-to-date test menu, KDL will no longer offer MTHFR genotyping.

The American College of Medical Genetics has a published Practice Guideline on MTHFR (see: https://www.acmg.net/docs/MTHFR_gim2012165a_Feb2013.pdf).

ACMG Recommendations Summarized:

  • MTHFR polymorphism genotyping should not be ordered as part of the clinical evaluation for thrombophilia or recurrent pregnancy loss.
  • MTHFR polymorphism genotyping should not be ordered for at-risk family members
  • MTHFR status does not change the recommendation that women of childbearing age should take the standard dose of folic acid supplementation.

We value your continued support of Knight Diagnostic Laboratories. If you have any questions, please do not hesitate to call. 

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Additional Info:

Molecular Diagnostics CLIA #38D0881787 Translational Research Lab CLIA #38D2018256 Q11-TSD-100.01